Alginate / Magnesium Carbonate

1. DailyMed — Alginate-Magnesium Reflux Suppressant Labelling

• Relief of occasional heartburn and acid reflux, particularly postprandial and nocturnal symptoms, or as an adjunct after meals and at bedtime alongside other GERD therapy.

• Considered a reasonable option for occasional use in pregnancy given minimal systemic absorption.

• Compatible with breastfeeding at usual doses.

• No specific dose adjustment at usual intermittent use; avoid regular high-dose use given magnesium accumulation risk with reduced renal clearance.

• Not generally first-line for chronic pediatric GERD; use only under guidance for pediatric dosing.

• 2-4 tablets chewed, or the equivalent liquid dose, after meals and at bedtime, as needed.

If overdose is suspected, seek emergency medical attention immediately or contact your regional Poison Control Centre without delay.

• Excessive use can cause diarrhea or gastrointestinal upset; seek medical attention for severe or persistent symptoms.

• Nausea, belching, flatulence.

Serious side effects require immediate discussion with the prescriber or emergency care.

• Magnesium accumulation with regular high-dose use in significant renal impairment.

• Aluminum-free alternative to the aluminum-hydroxide combination — still avoid regular high-dose use in significant renal impairment because of magnesium accumulation risk.

• Known hypersensitivity to any component.

• Reduces absorption of digoxin, tetracyclines, and fluoroquinolones — separate dosing by at least 2 hours.

• Take after meals and at bedtime for the best barrier effect.

• As needed, after meals and at bedtime.

• Store at room temperature; shake liquid formulations well before use.

• Works differently from typical antacids — it forms a protective raft over stomach contents rather than neutralizing acid, so take it after meals and at bedtime for the best effect.
• Separate from digoxin, tetracyclines, and quinolones by at least 2 hours.